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1

Preclinical Models of DNA Repair Deficiency in Prostate Cancer

Fitzpatrick, K., Hwang, J., Cai, M.Y., Liu, D., Kochupurakkal, B., Van Allen, E., DAndrea, A.D., Mouw, K.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2018

File:

PDF, 251 KB

2018

2

Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer

FÃ¤rkkilÃ¤, Anniina, Gulhan, Doga C., Casado, Julia, Jacobson, Connor A., Nguyen, Huy, Kochupurakkal, Bose, Maliga, Zoltan, Yapp, Clarence, Chen, Yu-An, Schapiro, Denis, Zhou, Yinghui, Graham, Julie R

Journal:

Nature Communications

Year:

2020

Language:

english

File:

PDF, 6.00 MB

english, 2020

3

Signal transduction and oncogenesis by ErbB/HER receptors

Mina D Marmor, Kochupurakkal Bose Skaria, Yosef Yarden

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2004

Language:

english

File:

PDF, 311 KB

english, 2004

4

Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling

Shtiegman, K, Kochupurakkal, B S, Zwang, Y, Pines, G, Starr, A, Vexler, A, Citri, A, Katz, M, Lavi, S, Ben-Basat, Y

Journal:

Year:

2007

Language:

english

File:

PDF, 456 KB

english, 2007

5

Trophoblast cells can induce regulatory T cells

N. Kochupurakkal, L. Chabtini, I. Guleria

Journal:

Journal of Reproductive Immunology

Year:

2012

Language:

english

File:

PDF, 72 KB

english, 2012

6

Nanog transforms NIH3T3 cells and targets cell-type restricted genes

Dan Piestun, Bose S. Kochupurakkal, Jasmine Jacob-Hirsch, Sharon Zeligson, Mark Koudritsky, Eytan Domany, Ninette Amariglio, Gideon Rechavi, David Givol

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 884 KB

english, 2006

7

Nanog inhibits the switch of myogenic cells towards the osteogenic lineage

Bose S. Kochupurakkal, Rachel Sarig, Ora Fuchs, Dan Piestun, Gidi Rechavi, David Givol

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 1.22 MB

english, 2008

8

The deaf and the dumb: the biology of ErbB-2 and ErbB-3

Ami Citri, Kochupurakkal Bose Skaria, Yosef Yarden

Journal:

Experimental Cell Research

Year:

2003

Language:

english

File:

PDF, 375 KB

english, 2003

9

Development of whey-fruit-based energy drink mixes using D-optimal mixture design

Shiby, Varghese Kochupurakkal, Radhakrishna, Kolpe, Bawa, Amarinder Singh

Journal:

International Journal of Food Science & Technology

Year:

2013

Language:

english

File:

PDF, 781 KB

english, 2013

10

B7h (ICOS-L) Maintains Tolerance at the Fetomaternal Interface

Riella, Leonardo V., Dada, Shirine, Chabtini, Lola, Smith, Brian, Huang, Lei, Dakle, Pranal, Mfarrej, Bechara, D'Addio, Francesca, Adams, La-Tonya, Kochupurakkal, Nora, Vergani, Andrea, Fiorina, Paolo

Journal:

The American Journal of Pathology

Year:

2013

Language:

english

File:

PDF, 1.19 MB

english, 2013

11

NF- B Activation-Induced Anti-apoptosis Renders HER2-Positive Cells Drug Resistant and Accelerates Tumor Growth

Bailey, S. T., Miron, P. L., Choi, Y. J., Kochupurakkal, B., Maulik, G., Rodig, S. J., Tian, R., Foley, K. M., Bowman, T., Miron, A., Brown, M., Iglehart, J. D., Biswas, D. K.

Journal:

Molecular Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.63 MB

english, 2014

12

Epigen, the Last Ligand of ErbB Receptors, Reveals Intricate Relationships between Affinity and Mitogenicity

Kochupurakkal, B. S., Harari, D., Di-Segni, A., Maik-Rachline, G., Lyass, L., Gur, G., Kerber, G., Citri, A., Lavi, S., Eilam, R., Chalifa-Caspi, V., Eshhar, Z., Pikarsky, E., Pinkas-Kramarski, R., Ba

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 1.10 MB

english, 2005

13

Chronic allograft rejection

Wedel, Johannes, Bruneau, Sarah, Kochupurakkal, Nora, Boneschansker, Leo, Briscoe, David M.

Journal:

Current Opinion in Organ Transplantation

Year:

2015

Language:

english

File:

PDF, 282 KB

english, 2015

14

Blockade of the Programmed Death-1 (PD1) Pathway Undermines Potent Genetic Protection from Type 1 Diabetes

Kochupurakkal, Nora M., Kruger, Annie J., Tripathi, Sudipta, Zhu, Bing, Adams, La Tonya, Rainbow, Daniel B., Rossini, Aldo, Greiner, Dale L., Sayegh, Mohamed H., Wicker, Linda S., Guleria, Indira, Ahm

Journal:

Year:

2014

Language:

english

File:

PDF, 1.23 MB

english, 2014

15

The Achilles Heel of ErbB-2/HER2: Regulation by the Hsp90 Chaperone Machine and Potential for Pharmacological Intervention

Citri, Ami, Kochupurakkal, Bose S., Yarden, Yosef

Journal:

Year:

2004

Language:

english

File:

PDF, 441 KB

english, 2004

16

Identification of genes responsible for RelA-dependent proliferation arrest in human mammary epithelial cells conditionally expressing RelA

Kochupurakkal, Bose S., Iglehart, J. Dirk

Journal:

Year:

2016

Language:

english

File:

PDF, 238 KB

english, 2016

17

Subtype-specific accumulation of intracellular zinc pools is associated with the malignant phenotype in breast cancer

Chandler, Paige, Kochupurakkal, Bose S., Alam, Samina, Richardson, Andrea L., Soybel, David I., Kelleher, Shannon L.

Journal:

Molecular Cancer

Year:

2016

Language:

english

File:

PDF, 2.28 MB

english, 2016

18

CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxin

Männ, Linda, Kochupurakkal, Nora, Martin, Christian, Verjans, Eva, Klingberg, Anika, Sody, Simon, Kraus, Andreas, Dalimot, Jill, Bergmüller, Eileen, Jung, Steffen, Voortman, Sylvia, Winterhager, Elke,

Journal:

European Journal of Immunology

Year:

2016

Language:

english

File:

PDF, 1.26 MB

english, 2016

19

Regulation of mTOR Signaling by Semaphorin 3F-Neuropilin 2 Interactions In Vitro and In Vivo

Nakayama, Hironao, Bruneau, Sarah, Kochupurakkal, Nora, Coma, Silvia, Briscoe, David M., Klagsbrun, Michael

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.90 MB

english, 2015

20

The intragraft microenvironment as a central determinant of chronic rejection or local immunoregulation/tolerance

Wedel, Johannes, Nakayama, Hironao, Kochupurakkal, Nora M., Koch, Josephine, Klagsbrun, Michael, Bielenberg, Diane R., Briscoe, David M.

Journal:

Current Opinion in Organ Transplantation

Year:

2016

Language:

english

File:

PDF, 408 KB

english, 2016

21

Nourseothricin N-Acetyl Transferase: A Positive Selection Marker for Mammalian Cells

Kochupurakkal, Bose S., Iglehart, J. Dirk, Almeida-Porada, Graca

Journal:

Year:

2013

Language:

english

File:

PDF, 1.40 MB

english, 2013

22

RelA-Induced Interferon Response Negatively Regulates Proliferation

Kochupurakkal, Bose S., Wang, Zhigang C., Hua, Tony, Culhane, Aedin C., Rodig, Scott J., Rajkovic-Molek, Koraljka, Lazaro, Jean-Bernard, Richardson, Andrea L., Biswas, Debajit K., Iglehart, J. Dirk, A

Journal:

Year:

2015

Language:

english

File:

PDF, 3.82 MB

english, 2015

23

Key Features of the Intragraft Microenvironment that Determine Long-Term Survival Following Transplantation

Bruneau, Sarah, Woda, Craig Bryan, Daly, Kevin Patrick, Boneschansker, Leonard, Jain, Namrata Gargee, Kochupurakkal, Nora, Contreras, Alan Gabriel, Seto, Tatsuichiro, Briscoe, David Michael

Journal:

Frontiers in Immunology

Year:

2012

Language:

english

File:

PDF, 1.35 MB

english, 2012

24

Olaparib and α-specific PI3K inhibitor alpelisib for patients with epithelial ovarian cancer: a dose-escalation and dose-expansion phase 1b trial

Konstantinopoulos, Panagiotis A, Barry, William T, Birrer, Michael, Westin, Shannon N, Cadoo, Karen A, Shapiro, Geoffrey I, Mayer, Erica L, O'Cearbhaill, Roisin E, Coleman, Robert L, Kochupurakkal, Bo

Journal:

The Lancet Oncology

Year:

2019

File:

PDF, 1.29 MB

2019

25

The CHK1 Inhibitor Prexasertib Exhibits Monotherapy Activity in High-Grade Serous Ovarian Cancer Models and Sensitizes to PARP Inhibition

Parmar, Kalindi, Kochupurakkal, Bose S., Lazaro, Jean-Bernard, Wang, Zhigang C., Palakurthi, Sangeetha, Kirschmeier, Paul T., Yang, Chunyu, Sambel, Larissa A., Färkkilä, Anniina, Reznichenko, Elizavet

Journal:

Clinical Cancer Research

Year:

2019

Language:

english

File:

PDF, 1.26 MB

english, 2019

26

A Novel Immunomodulatory Function for Semaphorin3F and Neuropilin-2 in Allograft Rejection.

Kochupurakkal, N., Nakayama, H., Demirci, G., Macleaod, K., Bielenberg, D., Klagsbrun, M., Briscoe, D.

Journal:

Transplantation Journal

Year:

2014

File:

PDF, 238 KB

2014

27

Novel Effects of Semaphorin 3F On the Regulation of Intracellular PI3K-Akt Signaling.

Nakayama, H., Bruneau, S., Kochupurakkal, N., Klagsbrun, M., Briscoe, D.

Journal:

Transplantation Journal

Year:

2014

File:

PDF, 181 KB

2014

28

T-Cell Specific Adapter Protein (TSAd) Mediates Immunoregulation in Alloimmunity.

Sheehan, M., Stack, M., Seto, T., Liu, K., McGourty, M., Kochupurakkal, N., Briscoe, D.

Journal:

Transplantation Journal

Year:

2014

File:

PDF, 200 KB

2014

29

NRP1 in Effector and Regulatory CD4+ T Cell Populations.

Lee, E., Kochupurakkal, N., Nakayama, H., Kim, H., Briscoe, D., Demirci, G.

Journal:

Transplantation Journal

Year:

2014

File:

PDF, 329 KB

2014

30

Cooperation of the ATM and Fanconi Anemia/BRCA Pathways in Double-Strand Break End Resection

Cai, Mu-Yan, Dunn, Connor E., Chen, Wenxu, Kochupurakkal, Bose S., Nguyen, Huy, Moreau, Lisa A., Shapiro, Geoffrey I., Parmar, Kalindi, Kozono, David, DâAndrea, Alan D.

Journal:

Year:

2020

Language:

english

File:

PDF, 5.10 MB

english, 2020

31

Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy in BRCA1/2-mutant metastatic breast cancer

Waks, Adrienne G., Cohen, Ofir, Kochupurakkal, Bose, Kim, Dewey, Dunn, Connor E., Buendia, Jorge Buendia, Wander, Seth, Helvie, Karla, Lloyd, Maxwell R., Marini, Lori, Hughes, Melissa E., Freeman, Sam

Journal:

Annals of Oncology

Year:

2020

File:

PDF, 3.23 MB

2020

32

ATM Loss Confers Greater Sensitivity to ATR Inhibition than PARP Inhibition in Prostate Cancer

Rafiei, Shahrzad, Fitzpatrick, Kenyon, Liu, David, Cai, Mu-Yan, Elmarakeby, Haitham A., Park, Jihye, Ricker, Cora, Kochupurakkal, Bose S., Choudhury, Atish D., Hahn, William C., Balk, Steven P., Hwang

Journal:

Cancer Research

Year:

2020

File:

PDF, 2.37 MB

2020

33

Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer

FÃ¤rkkilÃ¤, Anniina, Gulhan, Doga C., Casado, Julia, Jacobson, Connor A., Nguyen, Huy, Kochupurakkal, Bose, Maliga, Zoltan, Yapp, Clarence, Chen, Yu-An, Schapiro, Denis, Zhou, Yinghui, Graham, Julie R

Journal:

Nature Communications

Year:

2020

File:

PDF, 636 KB

2020